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Nyxoah announces the publication of first positive clinical data in an OSA patient suffering from Complete Concentric Collapse (CCC)


Nyxoah announces the publication of first positive clinical data in an OSA patient suffering from Complete Concentric Collapse (CCC)

Mont-Saint-Guibert, Belgium – 3rd March 2021 – Nyxoah SA (Euronext: NYXH) (“Nyxoah” or the “Company”), a health-technology company focused on the development and commercialization of innovative solutions and services to treat Obstructive Sleep Apnea (OSA), today announces the publication of an article presenting the first case of successful treatment of an OSA patient suffering from Complete Concentric Collapse (CCC) with Nyxoah’s unique Genio® bilateral neurostimulation solution1.

Patients suffering from Complete Concentric Collapse (CCC) currently amount for at least 30% of the existing OSA patient population. For now, these patients are contra-indicated for existing Hypoglossal Nerve Stimulation OSA therapies. Nyxoah is currently conducting the BETTER SLEEP study, that aims to assess the effectiveness of the Genio® system bilateral hypoglossal nerve stimulation for Complete Concentric Collapse (CCC) patients and to build clinical evidence for a potential therapeutic indication expansion.

Dr. Richard Lewis, leading author of this publication and Principal Investigator of the BETTER SLEEP studycommented: “This case demonstrates successful control of obstructive sleep apnea in a patient with Complete Concentric Collapse (CCC) of the redropalatal airway. Whilst the final results of the Better Sleep trial are yet to be completed, the results so far in the CCC patients indicate that the Genio® system could potentially be a treatment for OSA patients with CCC who are intolerant of CPAP. “

Olivier Taelman, Chief Executive Officer of Nyxoah, added: “I would like to thank Dr. Lewis and the Perth team for getting this manuscript published, since this is the first and promising step towards offering hypoglossal nerve stimulation to a cohort of OSA patients who are currently excluded from such therapy. We will be announcing the full results of our BETTER SLEEP study in May 2021. “

– ENDS –

For further information, please contact:


Milena Venkova, Corporate Communications Manager

[email protected]

+32 490 11 93 57

About Nyxoah

Nyxoah is a healthtech company focused on the development and commercialization of innovative solutions and services to treat Obstructive Sleep Apnea (OSA). Nyxoah’s lead solution is the Genio® system, a CE-validated, patient-centered, next generation hypoglossal neurostimulation therapy for OSA, the world’s most common sleep disordered breathing condition that is associated with increased mortality risk2 and comorbidities including cardiovascular diseases, depression and stroke .

Following the successful completion of the BLAST OSA study in patients with moderate to severe OSA, the Genio® system received its European CE Mark in 2019. The Company is currently conducting the BETTER SLEEP study in Australia and New Zealand for therapy indication expansion, the DREAM IDE pivotal study for FDA approval and a post-marketing EliSA study in Europe to confirm the long-term safety and efficacy of the Genio® system.

For more information, please visit

Caution – CE marked since 2019. Investigational device in the United States. Limited by US federal law to investigational use in the United States.

1 Lewis R, Le J, Czank C, Raux G. Control of OSA in a patient with CCC of soft palate using bilateral hypoglossal nerve stimulation. Clin Case Rep. 2021; 00: 1–3 LINK

2 Young T. et al: Sleep Disordered Breathing and Mortality: Eighteen-Year Follow-up of the Wisconsin Sleep Cohort, Sleep. 2008 Aug 1; 31 (8): 1071–1078

First positive clinical data in an OSA CCC patient

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I’m a mum – kids struggle with their left & right but I’ve got a hack that makes getting ready for school a breeze

A MUM has shared a genius hack to help children with putting their shoes on properly.

With just a few weeks left until the start of the new school year, it is important to ensure your kid is all ready for the big day.

3Offering a helping hand, Anita shared the hack on TikTokCredit: TIKTOK/miseenplace_au 3According to her, all you need to have a label with their first and last nameCredit: TikTok/@miseenplace_au/

However, whilst putting on a shirt or trousers is a task most of them seem to have mastered, there is one basic thing that's a struggle to many children - slipping into the right shoe.

Telling the right from the left is a task almost all of us found difficult growing up as well, and although there are plenty of parenting hacks that promise to help with this, one mum has gone viral after sharing her trick.

Anita Birges, from Australia, took it to TikTok to offer a helping hand to mums and dads across the world, as well as their offpsrings.

The parent, better known for her decluttering tips and tricks, said a lot of the times not only will the kid get confused with the right sides but will also eventually lose the shoes altogether.

According to Anita, her genius trick will solve both problems - so no more frustration and footwear that's gone missing.

''I have such a cool hack for you!

''Get a label with their first name and their last name on it. Cut it in half.

''Put their first name on the left hand side, the surname - on the right hand side.

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''Together, they spell their full name,'' she said, whilst demonstrating the parenting tip on a pair of black shoes.

The clip has been viewed more than 20,000 times and has seen fellow parents thank the whizz.

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One person wrote: ''that is a great idea, and because the names on the inside there's no embarrassment at school etc.''

Another commented: ''So smart trying this out.''

Someone else shared their hack: ''I draw a heart inside half in each shoe then they know it has to make a heart to be on the right foot.''

However, it wasn't all positive feedback, as a critic was convinced this trick wouldn't work for children of all ages.

''Usually kids who lose their shoes are too young so they cant even read [sic].''

3The genius hack has gone viral on social mediaCredit: TikTok/@miseenplace_au/

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